It only depends on your monitor resolution. It's all related to graphic card and not the game itself. Some games in the past were built NOT to expect higher resolutions, but then small and valuable patches came. Games as old as Diablo II and Quake III Arena can run as far as 1980x1080. I've been running both 1680x1050 becaue that is my capability of my monitor.
Well, Lunia should not be limited to any resolution changes. I'm not sure how it will affect the UI though. It gets smaller with each resolution increase. At 2000+ x 1500+ resolutions it might be to small to see properly lol.
I also don't recommended it as the higher your resolution is, they more demanding it is on your graphics card. Tell me what graphics card you have and I'll look for it's max possible resolution. Most basic cards are limited to 1280 x 1024. Also, make sure your monitor can handle the higher resolution. Trying to force a higher resolution on a monitor that can't handle it can severely damage it.