I use a gamepad to but it's the PS2 controller. I don't think I can help you with the X-Box controller setup.
I could show you what I use with my controller but I don't remember which buttons are what. I'll log on again tomorrow and then I'll most them here.
For F1 & F2 I use the shoulder buttons. I think it was L1 & R2.
For SP pots I use #0 on keyboard. It's not all very organized but it works for me.
I'll show you my setup tomorrow.
Also, I'm a Sword warrior and only use 1 (1st tree) skill tree. I have limited button use and using combo button means I have to sacrifice a button in order to even do combos. Right now for that, I trying out the select button as my combo button to use Edge Bounce and Counter. Works pretty well till I panic and mess up. xD
Anyways, till tomorrow then
Oh and 1-0 I use for emotes and random pots, sp pots & marcros. You can't set 1-0 on the controller. Doesn't work. At least, that's how it was the last time I tried it. That was back in August of last year.