Other than the Sleep-Bind combo, there aren't really any others where you would use S+Space, and even in the Sleep-Bind combo, it's not necessary. I just dash away and turn when I do that combo, works just as well. In some situations, it works better since you can make tiny adjustments to position before firing off Moon Pieces to make sure it's a direct hit. You can't do that if you use S+Space.
As far as movement goes in combos, normal shifting and half dashing is pretty much all you need for basic combos. For advanced ones, you may need to learn 4 key shifts.
"If someone asks you whether or not you're ticklish, it doesn't matter what you say, they're gonna touch you. If you don't wanna be touched, you gotta say something like, 'I have diarrhea. And yes, I'm very ticklish.'"