Originally Posted by Light
Unless you're an idiot and go to malicious websites, download sketchy looking files and torrents then you only really need the basics.
the absolute best defense is knowledge and knowing what you're doing when you use the internet.
That is pretty much all that anyone needs to learn.
As long as you're smart about what you do you really shouldn't run into issues.
But to answer your thread question, I use Avast + Malwarebytes + CCleaner. That's it.