Most of the time you don't need so much stuff.
Antivirus and Firewall should do just fine.
Most newer antivirus can scan for malware and some spyware, not perfect but there's some protection.
Not using Internet Explorer helps a lot as well. (I strongly recommend chrome for their sandbox)
Best practices are the best way to reduce such stuff.
1. Don't visit illegal, dodgy sites. *probably the best prevention of all
If your firefox or chrome says it isn't safe don't force your way into the website.
2. Don't run exe files that you have no idea what it is.
3. Keep your browser, operating system and antivirus up to date.
4. Don't disable UAC and don't click yes to UAC that you don't know what initiated it.
5. Disable USB autorun, autoplay
Another thing to note is that spyware and malware protection is really weak when you visit dodgy foreign sites like russia and china.
You can consider using sandboxie to sandbox your browser or sandbox any dodgy exe files that you intend to run, should be way less cpu/io intensive than having so many services.
Last edited by kag; 07-26-2012 at 09:12 AM.