Yea it looks like hardware error, you can remove the hard disk and backup the data.
Do a "chkdsk /F" or HDTune error scan when connecting to another PC to ensure that the harddisk is fine.
If it isn't then replace the hard disk and you should be good.
If it is, try to reinstall windows; if the error still occurs then something is dead.
Either RMA if there's still warranty or just buy a new one.