My main host's current specifications:
Intel Core 2 Duo E8400 (3GHz, 6MB L2 cache)
4GB DDR3-1333 RAM
ATI Radeon HD5570-based card
Windows 7 Enterprise 64-bit
I have had zero problems getting the program to run. All I am doing now is waiting on a good version of the installer which won't have the issue with Windows 7 that the current version does.
And a further note, if you have 64-bit hardware, use 64-bit Windows. You'll be a lot better off if you did. There is simply no reason to run 32-bit Windows anymore. Besides, you can only use the first 3GB on a 4GB system if you're using 32-bit Windows. Windows 64-bit will use it all.