I would like to remind everyone that you cannot eliminate network latency nor fully eliminate network spikes, just the same as you cannot break the laws of physics.
Electricity and light are fast, but on out Internet the maximum speed I've ever seen a packet traverse the US->UK gap is 120ms, which is always noticable for gaming. America will also have a sizeable lag if you're jumping from one side of the country to the other, or if you're having a heavy network load, simply from one state to the next. For the record, I suspect the physical server used by La Tale is located in Los Angeles (or at least it's hosting company is.)
You can speed up your own computer, but you cannot influence your switchboard and the worldwide web. You can also make sure that you don't get random Windows Updates hogging your bandwidth or other programs wanting to go online while you play, but you cannot stop intermittent failures or occasionally slow transferrals, resulting in spikes.
By all means try these mods, but do not expect miracles, because they will not provide those. And also be aware that these features are in Windows for a purpose: turning off QoS features will make already normally heavy programs like BitTorrent excruciatingly brutal on your connection, and will completely saturate your connection.